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Lawrence Scahill Selected Research

Guanfacine (Tenex)

1/2018A randomized, placebo-controlled trial of extended-release guanfacine in children with autism spectrum disorder and ADHD symptoms: an analysis of secondary outcome measures.
11/2017Extended-Release Guanfacine Does Not Show a Large Effect on Tic Severity in Children with Chronic Tic Disorders.
12/2015Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder.
2/2010Possible influence of variant of the P-glycoprotein gene (MDR1/ABCB1) on clinical response to guanfacine in children with pervasive developmental disorders and hyperactivity.
1/2009Alpha-2 adrenergic agonists in children with inattention, hyperactivity and impulsiveness.
8/2007alpha2-Adrenergic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: emerging concepts from new data.
11/2005An open-label, prospective study of guanfacine in children with ADHD and tic disorders.

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Lawrence Scahill Research Topics

Disease

26Autism Spectrum Disorder
01/2022 - 11/2005
23Autistic Disorder (Autism)
08/2017 - 08/2002
17Tics (Tic)
01/2022 - 01/2005
13Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2018 - 02/2005
11Tic Disorders (Tic Disorder)
01/2020 - 01/2003
10Weight Gain
01/2016 - 08/2002
8Tourette Syndrome (Tourette's Syndrome)
11/2017 - 04/2002
3Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2019 - 04/2006
3Fatigue
12/2015 - 08/2002
2Constipation
03/2020 - 12/2005
2Enuresis
08/2015 - 12/2005
2Schizophrenia (Dementia Praecox)
01/2015 - 08/2002
2Sleepiness
01/2009 - 12/2005
2Sialorrhea
12/2005 - 08/2002
1Anxiety Disorders (Anxiety Disorder)
01/2022
1Neurodevelopmental Disorders
10/2020
1Scurvy (Scorbutus)
06/2020
1Hoarding Disorder
01/2019
1Compulsive Personality Disorder (Obsessive Compulsive Personality)
01/2019
1Parasomnias (Parasomnia)
01/2018
1Insulin Resistance
01/2016
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2016
1Weight Loss (Weight Reduction)
11/2015
1Mental Disorders (Mental Disorder)
01/2015
1Fragile X Syndrome (Martin Bell Syndrome)
04/2014
1Sleep Initiation and Maintenance Disorders (Insomnia)
06/2009
1Pruritus (Itching)
06/2009
1Diarrhea
06/2009
1Oppositional Defiant Disorder
02/2007
1Asperger Syndrome (Asperger's Syndrome)
02/2007
1Seizures (Absence Seizure)
12/2005
1Rhinitis
12/2005
1Blindness (Hysterical Blindness)
12/2005
1Dyskinesias (Dyskinesia)
12/2005
1Sudden Death
03/2005
1Intellectual Disability (Idiocy)
01/2003
1Dizziness (Lightheadedness)
08/2002

Drug/Important Bio-Agent (IBA)

23Risperidone (Risperdal Consta)FDA LinkGeneric
12/2016 - 08/2002
8Antipsychotic Agents (Antipsychotics)IBA
11/2015 - 08/2002
7Guanfacine (Tenex)FDA LinkGeneric
01/2018 - 11/2005
4CitalopramFDA LinkGeneric
01/2022 - 06/2009
4Methylphenidate (Ritalin)FDA LinkGeneric
01/2017 - 02/2005
4Pharmaceutical PreparationsIBA
08/2015 - 06/2005
3SolutionsIBA
11/2020 - 01/2018
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2022 - 06/2009
26-pyruvoyltetrahydropterin synthase (PTPS)IBA
11/2021 - 01/2017
2Soaps (Soap)IBA
11/2021 - 06/2013
2ElementsIBA
01/2019 - 03/2013
2Biomarkers (Surrogate Marker)IBA
08/2017 - 01/2015
2(6- chloro- 1- (2- (dimethylamino)ethyl)indol- 3- yl)- spiro(1H- isobenzofuran- 3,4'- piperidine)- 1'- yl- methanoneIBA
08/2017 - 08/2017
2Vasopressins (Vasopressin)IBA
08/2017 - 08/2017
2LeptinIBA
01/2016 - 06/2004
1Folic Acid (Vitamin M)FDA LinkGeneric
10/2020
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
06/2020
1Suppositories (Vaginal Suppositories)IBA
03/2020
1P-2 (P 2)IBA
01/2020
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
08/2017
1Insulin (Novolin)FDA Link
01/2016
1Alanine Transaminase (SGPT)IBA
01/2016
1Glucose (Dextrose)FDA LinkGeneric
01/2016
1Hemoglobins (Hemoglobin)IBA
01/2016
1IronIBA
11/2015
1Indicators and Reagents (Reagents)IBA
07/2015
1A-factor (Streptomyces)IBA
07/2015
1gamma-Aminobutyric Acid (GABA)IBA
04/2014
1beta-cyclodextrin tetradecasulfate (CTDS)IBA
12/2013
1Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
07/2013
1Interleukin-1 (Interleukin 1)IBA
12/2011
1Interleukin-17 (Interleukin 17)IBA
12/2011
1InterferonsIBA
12/2011
1InterleukinsIBA
12/2011
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2011
1Epidermal Growth Factor (EGF)IBA
12/2011
1Interleukin-13IBA
12/2011
1Serotonin (5 Hydroxytryptamine)IBA
12/2010
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2010
1MercuryIBA
02/2009
1Clonidine (ST 155)FDA LinkGeneric
01/2009
1ProlactinIBA
02/2007
1ElectrolytesIBA
12/2005
1ziprasidone (Geodon)FDA Link
03/2005
1Dopamine (Intropin)FDA LinkGeneric
08/2002
1Serotonin ReceptorsIBA
08/2002
1Antinuclear AntibodiesIBA
04/2002
1AutoantibodiesIBA
04/2002

Therapy/Procedure

15Therapeutics
01/2022 - 08/2002
2Aftercare (After-Treatment)
01/2021 - 01/2015
1Deep Brain Stimulation
07/2007
1Drug Therapy (Chemotherapy)
04/2006
1Activities of Daily Living (ADL)
01/2005